Search results for "Adipose tissues"

showing 3 items of 3 documents

Lyophilized Maqui (Aristotelia chilensis) Berry Induces Browning in the Subcutaneous White Adipose Tissue and Ameliorates the Insulin Resistance in H…

2019

Maqui (Aristotelia Chilensis) berry features a unique profile of anthocyanidins that includes high amounts of delphinidin-3-O-sambubioside-5-O-glucoside and delphinidin-3-O-sambubioside and has shown positive effects on fasting glucose and insulin levels in humans and murine models of type 2 diabetes and obesity. The molecular mechanisms underlying the impact of maqui on the onset and development of the obese phenotype and insulin resistance was investigated in high fat diet-induced obese mice supplemented with a lyophilized maqui berry. Maqui-dietary supplemented animals showed better insulin response and decreased weight gain but also a differential expression of genes involved in de novo…

0301 basic medicineAnthocyaninFGF21Physiologymedicine.medical_treatmentClinical BiochemistryWhite adipose tissueWhite adipose tissueBiochemistryMaqui berryAnthocyanins0302 clinical medicinemaqui berrybiologyChemistryanthocyaninsHigh-fat diethigh-fat dietLipogenesisObesitatmedicine.medical_specialtyRatolins (Animals de laboratori)030209 endocrinology & metabolismfibroblast growth factor 21carbohydrate-responsive element binding protein bArticle03 medical and health sciencesAristotelia chilensisInsulin resistancewhite adipose tissueInternal medicinemedicineObesityCarbohydrate-responsive element-binding proteinMolecular BiologybrowningdelphinidinInsulinlcsh:RM1-950Adipose tissuesCell Biologybiology.organism_classificationmedicine.diseaseTeixit adipós030104 developmental biologyEndocrinologylcsh:Therapeutics. PharmacologyMice (Laboratory animals)AlimentsThermogenesisAntioxidants
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Extracellular vesicles do not mediate the anti-inflammatory actions of mouse-derived adipose tissue mesenchymal stem cells secretome

2021

Este artículo se encuentra disponible en la siguiente URL: https://www.mdpi.com/1422-0067/22/3/1375 Este artículo pertenece al número especial "The Role of Mesenchymal Stem Cells on Inflammatory and Fibrotic Diseases". Adipose tissue represents an abundant source of mesenchymal stem cells (MSC) for therapeutic purposes. Previous studies have demonstrated the anti-inflammatory potential of adipose tissue-derived MSC (ASC). Extracellular vesicles (EV) present in the conditioned medium (CM) have been shown to mediate the cytoprotective effects of human ASC secretome. Nevertheless, the role of EV in the anti-inflammatory effects of mouse-derived ASC is not known. The current study has investiga…

LipopolysaccharidesMaleChemokineLipopolysaccharideCélulas madre - Uso terapéutico.Adipose tissueInflammationmacrophageArticleCatalysisNitric oxideStem cells - Therapeutic use.lcsh:ChemistryInorganic ChemistryMicechemistry.chemical_compoundmedicineAnimalsMacrophageInflamación - Tratamiento.mesenchymal stem cells secretomePhysical and Theoretical ChemistryMacrophages.Receptorlcsh:QH301-705.5Molecular BiologyCells CulturedSpectroscopybiologyChemistryInflammation - Treatment.MacrophagesOrganic ChemistryMesenchymal stem cellmouse-derived adipose tissueMesenchymal Stem CellsGeneral MedicineAdipose tissues - Therapeutic use.Computer Science ApplicationsCell biologylcsh:Biology (General)lcsh:QD1-999inflammationMacrófagos.biology.proteinTejido adiposo - Uso terapéutico.medicine.symptomextracellular vesicles
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Dietary Inflammatory Index and liver status in subjects with different adiposity levels within the PREDIMED trial.

2018

Summary Background & aims To assess the possible association between a validated Dietary Inflammatory Index (DII) and specific dietary components with suitable non-invasive markers of liver status in overweight and obese subjects within the PREDIMED study. Methods A cross-sectional study encompassing 794 randomized overweight and obese participants (mean ± SD age: 67.0 ± 5.0 y, 55% females) from the PREDIMED (PREvencion con DIeta MEDiterranea) trial was conducted. DII is a validated tool evaluating the effect of diet on six inflammatory biomarkers (IL-1b, IL-4, IL-6, IL-10, TNF-α and C-reactive protein). Furthermore, a validated 137-item food-frequency-questionnaire was used to obtain the i…

MaleMediterranean dietPhysiologyDiseaseFetge -- MalaltiesOverweightCritical Care and Intensive Care MedicineDiet Mediterranean0302 clinical medicineNon-alcoholic Fatty Liver DiseaseSurveys and QuestionnairesAdiposityNutrition and DieteticsMalalties del fetgeFatty liverMiddle AgedInflamacióDiet RecordsC-Reactive ProteinLiver030220 oncology & carcinogenesisObesitatDieta030211 gastroenterology & hepatologyFemalemedicine.symptommedicine.medical_specialtyInflammation03 medical and health sciencesInternal medicineNAFLDmedicineHumansObesityLiver diseasesAgedInflammationbusiness.industryTumor Necrosis Factor-alphaInterleukinsAdipose tissuesAnthropometryOverweightmedicine.diseasePredimedObesityDietTeixit adipósEndocrinologyCross-Sectional StudiesPatient CompliancebusinessBiomarkers
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